Article

Characterization in mice of the stromal niche maintaining AT2 stem cell self-renewal in homeostasis and disease

2021-01-28

Abstract excerpt

Resident mesenchymal cells (rMCs defined as Cd31 Neg Cd45 Neg Epcam Neg ) control the self-renewal and differentiation of alveolar epithelial type 2 (AT2) stem cells in vitro. The identity of these rMCs is still elusive. Among them, Axin2 Pos mesenchymal alveolar niche cells (MANCs), which are expressing Fgf7, have been previously described. We propose that an additional population of rMCs, expressing Fgf10 (c...

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Literature Corpus work: a02e55d9-1aae-561e-a60c-b8fe65cd75c7
DOI: 10.1101/2021.01.28.428090

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