Article

scGenePT: Is language all you need for modeling single-cell perturbations?

2024-10-28

Abstract excerpt

Modeling single-cell perturbations is a crucial task in the field of single-cell biology. Predicting the effect of up or down gene regulation or drug treatment on the gene expression profile of a cell can open avenues in understanding biological mechanisms and potentially treating disease. Most foundation models for single-cell biology learn from scRNA-seq counts, using experimental data as a modality to generate...

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Literature Corpus work: a019230e-f39a-54b5-b6f9-6183ca15c03e
DOI: 10.1101/2024.10.23.619972

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