Large Scale Foundation Model on Single-cell Transcriptomics

Abstract excerpt

Large-scale pretrained models have become foundation models leading to breakthroughs in natural language processing and related fields. Developing foundation models in life science for deciphering the “languages” of cells and facilitating biomedical research is promising yet challenging. We developed a large-scale pretrained model scFoundation with 100M parameters for this purpose. scFoundation was trained on over...

Topics

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• Aging
• Cluster Analysis
• COVID-19
• Deep Learning
• Leukocytes, Mononuclear
• Phenotype
• Single-Cell Analysis
• Single-Cell Gene Expression Analysis

Identifiers and source

Literature Corpus work

d9e95558-1a88-5825-9db4-c9ab33a89a55

DOI

10.1101/2023.05.29.542705