Article

Tokenizing single-cell transcriptomes as a native language for large language models

2025-10-24

Abstract excerpt

Large language models (LLMs) can process diverse forms of information once they are represented as tokens in a shared sequence space. However, single-cell transcriptomes remain a foreign modality to LLMs because they are continuous, high-dimensional molecular profiles rather than discrete linguistic units. Here, we propose CellTok, a tokenized single-cell language modeling approach that converts transcriptomic pro...

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Literature Corpus work: 9aaa2535-7d79-54f9-b17a-5a441e2f2e60
DOI: 10.1101/2025.10.22.684047

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