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Article

Molecular Insights Into the Interaction of HPV-16 E6 Variants Against MAGI-1 PDZ1 Domain

2021-11-02

Abstract excerpt

Oncogenic protein E6 from Human Papilloma Virus 16 (HPV-16) mediates the degradation of Membrane-associated guanylate kinase with inverted domain structure-1 (MAGI-1), throughout the interaction of its protein binding motif (PBM) with the Discs-large homologous regions 1 (PDZ1) domain of MAG1-1. Generic variation in the E6 gene that translates to changes in the protein’s amino acidic sequence modifies the interact...

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Literature Corpus work
9fd6bc30-74f2-5f2b-8c8b-d219b3426347
DOI
10.21203/rs.3.rs-1009572/v1
Open publication

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Molecular Insights Into the Interaction of HPV-16 E6 Variants Against MAGI-1 PDZ1 DomainDOI 10.21203/rs.3.rs-1009572/v1
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