Article

Virus-host protein-protein interactions between human papillomavirus 16 E6 A1 and D2/D3 sub-lineages: variances and similarities

2020-06-26

Abstract excerpt

High-risk strains of human papillomavirus are causative agents for cervical and other mucosal cancers with type 16 being the most frequent. Compared to the European Prototype (A1, denoted “EP”), the Asian-American (D2/D3, denoted “AA”) sub-lineage or “variant” is reported to have increased abilities to promote carcinogenesis. Few global interactome studies have looked at protein-protein interactions (PPIs) between...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2992f29f-f742-5353-b875-8f305b00e9fc
DOI: 10.1101/2020.06.26.169458

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Virus-host protein-protein interactions between human papillomavirus 16 E6 A1 and D2/D3 sub-lineages: variances and similaritiesDOI 10.1101/2020.06.26.169458Read

Virus-Host Protein-Protein Interactions between Human Papillomavirus 16 E6 A1 and D2/D3 Sub-Lineages: Variances and Similarities.Semantic proximity Read

Functional variants of human papillomavirus type 16 demonstrate host genome integration and transcriptional alterations corresponding to their unique cancer epidemiology.Semantic proximity Read

Large scale genotype comparison of human papillomavirus E2-host interaction networks provides new insights for e2 molecular functions.Semantic proximity Read

Comprehensive Analysis of Host Cellular Interactions with Human Papillomavirus E6 Proteins Identifies New E6 Binding Partners and Reflects Viral DiversitySemantic proximity Read

E6AP is important for HPV E6’s role in regulating epithelial homeostasis and its loss impairs keratinocyte commitment to differentiationSemantic proximity Read

Structure of High-Risk Papillomavirus 31 E6 Oncogenic Protein and Characterization of E6/E6AP/p53 Complex FormationSemantic proximity Read

Structural and Functional Analysis of E6 Oncoprotein: Insights in the Molecular Pathways of Human Papillomavirus-Mediated PathogenesisSemantic proximity Read

Digital RNA Sequencing of Human Epidermal Keratinocytes Carrying Human Papillomavirus Type 16 E7Semantic proximity Read

Multiple Routes to Oncogenesis Are Promoted by the Human Papillomavirus-Host Protein Network.Semantic proximity Read

HPV16 Status Predicts Differential Interactome in Head and Neck Squamous Cell Carcinoma: Potential Prognostic Biomarkers and Therapeutics in Framework of 3P MedicineSemantic proximity Read

Tumourigenesis Driven by the Human Papillomavirus Type 16 Asian-American E6 Variant in a Three-Dimensional Keratinocyte ModelSemantic proximity Read

The Role of HPV E6 and E7 Oncoproteins in HPV-associated Cervical CarcinogenesisSemantic proximity Read