Article

A guide to examining intramuscular fat formation and its cellular origin in skeletal muscle

2022-03-07

Abstract excerpt

<h4>ABSTRACT</h4> Fibro-adipogenic progenitors (FAPs) are mesenchymal stromal cells that play a crucial role during skeletal muscle homeostasis and regeneration. FAPs build and maintain the extracellular matrix that acts as a molecular myofiber scaffold. In addition, FAPs are indispensable for myofiber regeneration as they secrete a multitude of beneficial factors sensed by the muscle stem cells (MuSCs). In disea...

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Literature Corpus work: dd260527-e10a-52dd-b3cd-5d736deaffa6
DOI: 10.1101/2022.03.06.483182

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