Article

Paradoxes in the Ontological Classification of Glia- Evidence for an Important New Class of Brain Cells with Primary Functions in Iron Regulation

2025-04-23

Abstract excerpt

The ontological categorization of the cellular elements of the brain was proposed over a century ago by Santiago Ramón y Cajal (neurons, astroglia) and Pío del Río-Hortega (oligodendroglia, microglia). It combines histochemical observations of morphology with allied inferences about the specialized functions and origins (ectoderm or mesoderm) of each cellular element. This ontology shapes mode...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9fba2307-f653-58fa-b3f9-c47b6937bfb2
DOI: 10.20944/preprints202504.1996.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Paradoxes in the Ontological Classification of Glia- Evidence for an Important New Class of Brain Cells with Primary Functions in Iron RegulationDOI 10.20944/preprints202504.1996.v1Read

Single-cell Transcriptomics Analyses Revealed Specialized Microglial Subsets with Oligodendrocyte-like SignaturesSemantic proximity Read

Oligodendrocyte Development and Myelination in Neurodevelopment: Molecular Mechanisms in Health and DiseaseSemantic proximity Read

Astrocytes in Alzheimer´s Disease: Pathological Significance and Molecular PathwaysSemantic proximity Read

Neurodegenerative Diseases: Unraveling the Heterogeneity of Astrocytes.Semantic proximity Read

Regionally encoded functional heterogeneity of astrocytes in health and disease: A perspective.Semantic proximity Read

Diversity of astrocyte functions and phenotypes in neural circuits.Semantic proximity Read

Astrocytes in Alzheimer’s Disease: Pathological Significance and Molecular PathwaysSemantic proximity Read

Rethinking Intellectual Disability from Neuro- to Astro-Pathology.Semantic proximity Read

Motor System Oligodendroglia Atlas Reveals Activation States Associated with Region-Specific Vulnerability in ALSSemantic proximity Read

FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer’s Disease: Evidence from Single-Cell Transcriptomic AnalysisSemantic proximity Read

Motor System Oligodendroglia Atlas Reveals Activation States Associated with Region-Specific Vulnerability in ALSSemantic proximity Read

Single-cell sequencing unravels the cellular diversity that shapes neuro- and gliogenesis in the fast aging killifish ( <i>N. furzeri</i> ) brainSemantic proximity Read