Article

Single-cell sequencing unravels the cellular diversity that shapes neuro- and gliogenesis in the fast aging killifish ( <i>N. furzeri</i> ) brain

2021-07-04

Abstract excerpt

<h4>Summary</h4> The African turquoise killifish combines a short lifespan with spontaneous age-dependent loss of neuroregenerative capacity. The stem cell niches driving neuroregeneration and their molecular signatures remain elusive. To investigate this, we performed scRNA-seq of the adult telencephalon, combined with full-length transcriptomics using ISO-seq. Our results unveil about 25 cell types including ne...

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Literature Corpus work: 29432f5d-64eb-5130-b6ec-27446599d97c
DOI: 10.1101/2021.07.04.450918

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