Article

Transposon invasion of primate genomes shaped human inflammatory enhancers and susceptibility to inflammatory diseases

2025-01-22

Abstract excerpt

Human immune inflammatory response reflects the evolutionary adaptation of immune-cell regulatory elements 1 , where recent mutations can control both pathogen defence and susceptibility to chronic inflammatory and autoimmune diseases 2–4 . The impact of the deeper evolutionary history of these elements within primate genomes on human inflammatory responses remains poorly understood. Evolutionary young transposo...

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Literature Corpus work: 9f6276eb-13ff-5f43-9d3e-f83e4e520e55
DOI: 10.1101/2025.01.21.632732

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