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Neutrophils activated by cancer cells and M2 macrophages promote gastric cancer progression during PD-1 antibody-based immunotherapy

2022-04-19

Abstract excerpt

Biomarkers of immune checkpoint inhibitors (ICIs) in advanced gastric cancer (AGC) are under investigation. In present study, correlation between neutrophil-to-lymphocyte ratio (NLR) and efficacy of ICIs treatment in AGC patients as well as its underlying mechanisms were investigated based on clinical cases and single-cell RNA sequencing (scRNA-seq) analysis. NLRs early after treatment were correlated with disease...

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Literature Corpus work
9f4f2bc3-d98d-5b7c-8945-4958050bc2f6
DOI
10.21203/rs.3.rs-1556189/v1
Open publication

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Neutrophils activated by cancer cells and M2 macrophages promote gastric cancer progression during PD-1 antibody-based immunotherapyDOI 10.21203/rs.3.rs-1556189/v1
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