Article

Long-chain polyphosphates impair SARS-CoV-2 infection and replication: a route for therapy in man

2020-11-18

Abstract excerpt

Anti-viral activities of long-chain inorganic polyphosphates (PolyPs) against severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection were investigated. In molecular docking analyses, PolyPs interacted with several conserved angiotensin-converting enzyme (ACE)2 and RNA-dependent RNA polymerase (RdRp) amino acids. We thus tested PolyPs for functional interactions in vitro in SARS-CoV-2–infected Vero E...

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Literature Corpus work: 9f2d94e3-4ebf-52ce-8e2c-a7ca63020130
DOI: 10.1101/2020.11.18.388413

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