Article

Encapsulation of Recombinant ACE-2 in Chitosan Nanoparticles for Treatment of SARS-CoV-2 Infection

2025-02-08

Abstract excerpt

COVID-19 infection continues globally with frequent emergence of unfamiliar SARS-CoV-2 variants acting to impair immunity conferred by vaccines. The competitive binding of SARS-CoV-2 spike proteins by angiotensin-converting enzyme 2 (ACE-2) to mimetic and act as a de-coy over that by native ACE-2 receptors on healthy human cells re-mains a practical approach to lessen viral spread. In this study, a therapeutic str...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d67a492e-b064-53c4-aa7c-951ee8b31494
DOI: 10.20944/preprints202502.0602.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Encapsulation of Recombinant ACE-2 in Chitosan Nanoparticles for Treatment of SARS-CoV-2 InfectionDOI 10.20944/preprints202502.0602.v1Read

Inhalable nanocatchers for SARS-CoV-2 inhibitionSemantic proximity Read

Rapid generation of circulating and mucosal decoy ACE2 using mRNA nanotherapeutics for the potential treatment of SARS-CoV-2Semantic proximity Read

Host-Directed Virus-Mimicking Particles Interacting with the ACE2 Receptor Competitively Block Coronavirus SARS-CoV-2 EntrySemantic proximity Read

Formulation development and comparability studies with an aluminum-salt adjuvanted SARS-CoV-2 Spike ferritin nanoparticle vaccine antigen produced from two different cell linesSemantic proximity Read

Novel ACE2 nanoparticles universally block SARS-CoV-2 variants in the human respiratory tractSemantic proximity Read

Low Molecular Weight Sulfated Chitosan Efficiently Reduces Infection Capacity of Porcine Circovirus Type 2 (PCV2) In PK15 CellsSemantic proximity Read

Chitosan derivatives: A suggestive evaluation for novel inhibitor discovery against wild type and variants of SARS-CoV-2 virus.Semantic proximity Read

Cold atmospheric plasma for preventing infection of viruses that use ACE2 for entrySemantic proximity Read

Introduction of Two Prolines and Removal of the Polybasic Cleavage Site Lead to Higher Efficacy of a Recombinant Spike-Based SARS-CoV-2 Vaccine in the Mouse Model.Semantic proximity Read

Long-chain polyphosphates impair SARS-CoV-2 infection and replication: a route for therapy in manSemantic proximity Read

Plastic Antibodies Mimicking the ACE2 Receptor for Selective Binding of SARS‐CoV‐2 SpikeSemantic proximity Read

Engineering mesenchymal stem cells with neutralizing and anti- inflammation dual-capability against SARS-CoV-2 infectionSemantic proximity Read