Article

Intersection of Regulatory Analysis and Signature Reversion Uncovers Therapeutic Drugs and Targets for <i>SETBP1</i> -HD

2026-05-26

Abstract excerpt

<h4>Background</h4> SETBP1 haploinsufficiency disorder ( SETBP1 -HD) is a neurodevelopmental condition characterized by developmental delay, speech apraxia, motor deficits, and autism spectrum disorder (ASD), caused by deficiency of the transcription factor (TF) SETBP1. Since current management is limited to symptomatic relief, we defined a robust consensus molecular signature for SETBP1 -HD and prioritized dru...

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Literature Corpus work: 9f27d397-c1f0-5903-9088-1b8b0102cfed
DOI: 10.64898/2026.05.21.726884

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