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A Boolean Model of the Formation of Tumour Associated Macrophages in an <i>in-vitro</i> Model of Chronic Lymphocytic Leukaemia

2020-10-15

Abstract excerpt

The tumour microenvironment is the collection of cells in and surrounding cancer cells in a tumour including a variety of immune cells, especially neutrophils and monocyte-derived macrophages. In a tumour setting, macrophages encompass a spectrum between a tumour-suppressive (M1) or tumour-promoting (M2) state. The biology of macrophages found in tumours (Tumour Associated Macrophages) remains unclear, but underst...

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Literature Corpus work
9f0f140c-19f0-58f1-a11c-8852d68041de
DOI
10.1101/2020.10.14.337642
Open publication

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