Article

ADAM17 regulates hepatic DNA damage repair and tumour formation

2024-07-30

Abstract excerpt

<h4>Background</h4> Hepatocellular carcinoma (HCC) is one of the leading causes of cancer deaths worldwide. Still, therapy options for this tumour entity are limited and novel therapeutic options are highly sought after. Genomic instability of hepatocytes promotes oncogenic transformation and underlies the regulation of micro-environmental signalling cues. The membrane-bound a disintegrin and metalloprotease (ADA...

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Literature Corpus work: 9ef8b8f1-7a5b-5909-8820-5ff6fe7e3e56
DOI: 10.1101/2024.07.30.605791

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