Article

Unique nigral and cortical pathways implicated by epigenomic and transcriptional analyses in a rotenone rat model of Parkinson’s disease

2024-12-20

Abstract excerpt

Pesticide exposure is increasingly recognised as a potential environmental factor contributing to the onset of idiopathic Parkinson’s disease, yet the molecular mechanisms underlying this connection remain unclear. This study aims to explore how pesticide exposure disrupts key brain regions involved in Parkinson’s disease pathology by reshaping gene regulatory landscapes. Using the well-established rotenone rat mo...

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Literature Corpus work: 9ef4dca9-3624-5461-8628-8af8d765e9dd
DOI: 10.1101/2024.12.17.628873

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