Article
Comparing the efficacy of cancer therapies between subgroups in basket trials
2018-08-28
Abstract excerpt
<h4>SUMMARY</h4> An increase in the number of targeted anti-cancer drugs and growing genomic stratification of patients has led to the development of basket clinical trials in which a single drug is tested simultaneously in multiple tumor subtypes under a master protocol. Basket trials typically involve few patients per type, making it difficult to rigorously compare responses across types. We describe the use of...
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Identifiers and source
- Literature Corpus work
- 9eb34f5a-0649-5d7e-b481-9763461439e8
- DOI
- 10.1101/401620