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Article

Tumor-Specific Activity of Precision Medicines in the NCI-MATCH Trial.

Clinical cancer research : an official journal of the American Association for Cancer Research - 16 Feb 2024

Zhou Ivvone, Plana Deborah, Palmer Adam C

Abstract excerpt

PURPOSE: National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH) is a precision medicine basket trial designed to test the effectiveness of treating cancers based on specific genetic changes in patients' tumors, regardless of cancer type. Multiple subprotocols have each tested different targeted therapies matched to specific genetic aberrations. Most subprotocols exhibited low rates of tumor...

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Identifiers

PMID: 38109210
DOI: 10.1158/1078-0432.CCR-23-0983
PMCID: PMC10922532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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