Article

Evolving or Immutable - Phase I Solid Tumor Trials in the Era of Precision Oncology

2024-04-29

Abstract excerpt

<title>Abstract</title> <p>Purpose In the era of precision oncology (PO), systemic therapies for patients (pts) with solid tumors have shifted from chemotherapy (CT) to targeted therapy (TT) and immunotherapy (IO). This systematic survey describes features of trials enrolling between 2010-2020, focusing on inclusion criteria, type of dose escalation scheme (DES) utilized, and use of expansion cohorts (ECs). Metho...

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Literature Corpus work: d2048adf-38a6-522d-a1fc-97b4e5a3ba2c
DOI: 10.21203/rs.3.rs-4202155/v1

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