Article

Decipher macrophage-fibroblast-cardiomyocyte signaling interactions associated with heart failure using deep graph neural network models and single-cell RNA-seq data

2022-11-04

Abstract excerpt

Heart failure is a major cause of mortality. In these recent studies, novel evidence, using single-cell transcriptomic data, was reported to indicate that macrophages and fibroblasts play important roles in heart failure. The involvement of macrophages in inflammation and the relationship between inflammation and fibrosis has been established. However, the underlying molecular targets and signaling pathways mediat...

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Literature Corpus work: 9e9b7c92-417d-5a40-93b0-4a3d7d71d80d
DOI: 10.1101/2022.11.02.514928

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