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Single cell study of cellular diversity and mutual communication in chronic heart failure and drug repositioning

24 Feb 2022

Abstract excerpt

Non-cardiomyocytes (non-CMs) play an important role in the process of cardiac remodeling of chronic heart failure. The mechanism of non-CMs transit and interact with each other remains largely unknown. Here, we try to characterize the cellular landscape of non-CMs in mice with chronic heart failure by using single-cell RNA sequencing (scRNA-seq) and provide potential therapeutic hunts. Cellular and molecular...

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PMID: 35219850
DOI: 10.1016/j.ygeno.2022.110322

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