Article

Parsimonious EBM: generalising the event-based model of disease progression for simultaneous events

2022-07-11

Abstract excerpt

This study introduces the parsimonious event-based model of disease progression (P-EBM). The P-EBM generalises the event-based model of disease progression (EBM) to allow inference of fewer disease progression stages than the number of input biomarkers. The original EBM is designed to estimate a single distinct biomarker abnormality, termed an event, at each model stage. By allowing multiple events within a common...

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Literature Corpus work: 9e99d6f2-4dab-50d2-839c-673e650c5442
DOI: 10.1101/2022.07.10.499471

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