Article

Spatio-Temporal Multi-Omics Profiling of Mechanisms and Biomarkers in Inhaled Drug-Induced Lung Toxicity

2025-11-21

Abstract excerpt

Comprehensive understanding and early detection of drug-induced lung toxicity remain critical challenges in respiratory drug development. In this study, we propose a multi-omics framework that integrates spatial and temporal tissue-specific transcriptomic signatures with proteomics from minimally invasive biofluids to understand mechanisms and identify safety biomarkers associated with lung toxicity. Using this fr...

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Literature Corpus work: 9e58ada6-d0c2-5fb7-97e6-b0cdf815dbd4
DOI: 10.1101/2025.11.20.689571

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Spatio-Temporal Multi-Omics Profiling of Mechanisms and Biomarkers in Inhaled Drug-Induced Lung ToxicityDOI 10.1101/2025.11.20.689571Read

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