Article
Application of 'omics technologies to biomarker discovery in inflammatory lung diseases.
The European respiratory journal - 1 Sept 2013
Wheelock Craig E, Goss Victoria M, Balgoma David, Nicholas Ben, Brandsma Joost, Skipp Paul J, Snowden Stuart, Burg Dominic, D'Amico Arnaldo, Horvath Ildiko, Chaiboonchoe Amphun, Ahmed Hassan, Ballereau Stéphane, Rossios Christos, Chung Kian Fan, Montuschi Paolo, Fowler Stephen J, Adcock Ian M, Postle Anthony D, Dahlén Sven-Erik, Rowe Anthony, Sterk Peter J, Auffray Charles, Djukanovic Ratko
Abstract excerpt
Inflammatory lung diseases are highly complex in respect of pathogenesis and relationships between inflammation, clinical disease and response to treatment. Sophisticated large-scale analytical methods to quantify gene expression (transcriptomics), proteins (proteomics), lipids (lipidomics) and metabolites (metabolomics) in the lungs, blood and urine are now available to identify biomarkers that define disease in...
Topics
- Biomarkers
- Breath Tests
- Bronchoalveolar Lavage Fluid
- Chromatography, Liquid
- Gene Expression Profiling
- Humans
- Inflammation
- Lipid Metabolism
