Article
Omics in Nonsteroidal Anti‐Inflammatory Drugs‐Exacerbated Respiratory Disease: Current Evidence From the Upper and Lower Airways
4 Sept 2025
Abstract excerpt
Nonsteroidal anti-inflammatory drugs (NSAID)-exacerbated respiratory disease (N-ERD) is a mainly type 2 inflammatory condition that combines asthma, nasal polyps, and hypersensitivity to NSAIDs. Its pathogenesis involves both upper and lower airways, yet most studies to date have examined these compartments separately. It remains unclear whether the molecular mechanisms in the nose, sinuses, and lungs are...
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