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Adverse childhood experiences and recent negative events activate immune and growth factor pathways, which are associated with first episode major depression and suicidal behaviours

2023-06-27

Abstract excerpt

<h4>Background</h4> Adverse Childhood Experiences (ACEs) and Negative Life Events (NLEs) may activate immune-inflammatory pathways, which play a role in the onset of Major Depressive Disorder and its severe phenotype Major Dysmood disorder (MDMD). <h4>Objectives</h4> To assess if elevated ACEs and NLEs in first episode (FE)-MDMD predict activation of the immune-inflammatory response system (IRS), chemokines, and g...

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Literature Corpus work
9e308e7d-3bec-55b2-adaa-ebefd36cce8f
DOI
10.1101/2023.06.19.23291597
Open publication

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Adverse childhood experiences and recent negative events activate immune and growth factor pathways, which are associated with first episode major depression and suicidal behavioursDOI 10.1101/2023.06.19.23291597
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