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In severe first episode major depressive disorder, psychosomatic, chronic fatigue syndrome, and fibromyalgia symptoms are driven by immune activation and increased immune-associated neurotoxicity

2023-08-09

Abstract excerpt

<h4>Background</h4> Major depressive disorder (MDD) is accompanied by activated neuro-immune pathways, increased physiosomatic and chronic fatigue-fibromyalgia (FF) symptoms. The most severe MDD phenotype, namely major dysmood disorder (MDMD), is associated with adverse childhood experiences (ACEs) and negative life events (NLEs) which induce cytokines/chemokines/growth factors. <h4>Aims</h4> To delineate the im...

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Literature Corpus work
30bf45ba-8ab2-5420-92ab-cd09eec0e19a
DOI
10.1101/2023.08.06.23293708
Open publication

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In severe first episode major depressive disorder, psychosomatic, chronic fatigue syndrome, and fibromyalgia symptoms are driven by immune activation and increased immune-associated neurotoxicityDOI 10.1101/2023.08.06.23293708
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