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Interleukin-12 Dynamic Changes as a Predictive Biomarker of Antidepressant Response in Adolescents with MDD and Comorbid NSSI: A Prospective Longitudinal Study

2026-07-27

Abstract excerpt

<title>Abstract</title> <p> Background Non-suicidal self-injury (NSSI) is highly prevalent in adolescents with major depressive disorder (MDD) and poses a critical public health threat. While inflammatory dysregulation is implicated in both conditions, dynamic cytokine changes during treatment and their predictive value for therapeutic response remain unclear, especially for interleukin-12 (IL-12). Methods Thi...

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Literature Corpus work
007b9900-324b-5239-9ed5-4687fc1f3124
DOI
10.21203/rs.3.rs-10302761/v1
Open publication

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Interleukin-12 Dynamic Changes as a Predictive Biomarker of Antidepressant Response in Adolescents with MDD and Comorbid NSSI: A Prospective Longitudinal StudyDOI 10.21203/rs.3.rs-10302761/v1
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