Article

A common molecular mechanism for cognitive deficits and craving in alcoholism

2020-07-14

Abstract excerpt

Alcohol-dependent patients commonly show impairments in executive functions that facilitate craving and can lead to relapse. The medial prefrontal cortex, a key brain region for executive control, is prone to alcohol-induced neuroadaptations. However, the molecular mechanisms leading to executive dysfunction in alcoholism are poorly understood. Here using a bi-directional neuromodulation approach we demonstrate a...

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Literature Corpus work: 9dd3ca6e-88cb-51fa-bbc4-83bf6b648888
DOI: 10.1101/2020.07.13.200519

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