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Integrative Analysis of DNA Methylation Identified 12 Signature Genes Specific to Metastatic ccRCC

8 Oct 2020

Abstract excerpt

Background: Abnormal epigenetic alterations can contribute to the development of human malignancies. Identification of these alterations for early screening and prognosis of clear cell renal cell carcinoma (ccRCC) has been a highly sought-after goal. Bioinformatic analysis of DNA methylation data provides broad prospects for discovery of epigenetic biomarkers. However, there is short of exploration of...

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PMID: 33134164
DOI: 10.3389/fonc.2020.556018

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