Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-throughput screen identifies non inflammatory small molecule inducers of trained immunity

8 Jul 2024

Abstract excerpt

Trained immunity is characterized by epigenetic and metabolic reprogramming in response to specific stimuli. This rewiring can result in increased cytokine and effector responses to pathogenic challenges, providing nonspecific protection against disease. It may also improve immune responses to established immunotherapeutics and vaccines. Despite its promise for next-generation therapeutic design, most current...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Impact on Reproduction
Share to Epigenetics and DNA Methylation
Share to Immune responses and vaccinations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38976741
DOI: 10.1073/pnas.2400413121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-throughput screen identifies non inflammatory small molecule inducers of trained immunityPMID 38976741Read ↗

Trained immunity as a novel therapeutic strategySemantic proximity Read ↗

The causes and consequences of trained immunity in myeloid cellsSemantic proximity Read ↗

Trained immunity: General and emerging conceptsSemantic proximity Read ↗

BCG-Induced Immune Training: Interplay between Trained Immunity and Emergency GranulopoiesisSemantic proximity Read ↗

Infection-induced trained immunity: a twist in paradigm of innate host defense and generation of immunological memorySemantic proximity Read ↗

Trained immunity: adaptation within innate immune mechanismsSemantic proximity Read ↗

Trained immunity: A Yin‐Yang balanceSemantic proximity Read ↗

β-glucan induced trained immunity enhances antibody levels in a vaccination model in miceSemantic proximity Read ↗

β-Glucan-Induced Trained Immunity in DogsSemantic proximity Read ↗

Trained Innate Immunity Not Always AmicableSemantic proximity Read ↗

The mechanisms and cross-protection of trained innate immunitySemantic proximity Read ↗

Interleukin-10 inhibits important components of trained immunity in human monocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.