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Article

Trained immunity: implications for vaccination

18 May 2022

Abstract excerpt

The concept that only adaptive immunity can build immunological memory has been challenged in the past decade. Live attenuated vaccines such as the Bacillus Calmette-Guérin, measles-containing vaccines, and the oral polio vaccine have been shown to reduce overall mortality beyond their effects attributable to the targeted diseases. After an encounter with a primary stimulus, epigenetic and metabolic reprogramming...

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Identifiers

PMID: 35597182
DOI: 10.1016/j.coi.2022.102190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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