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Disruption of Marrow Microenvironments in Chronic Lymphocytic Leukemia by High-Resolution Synchrotron Micro-Computed Tomography

2025-10-21

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is associated with increased fracture risk unexplained by standard bone density scans, suggesting underlying microstructural alterations. To investigate this, we used high-resolution synchrotron micro-computed tomography (SRµCT) on bone marrow biopsies from 17 CLL patients, who were stratified into low and high infiltration groups using objective, data-driven clustering. To our k...

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Literature Corpus work
9d83c319-7e02-5092-8796-b4b8da953ae2
DOI
10.1101/2025.10.20.683519
Open publication

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Disruption of Marrow Microenvironments in Chronic Lymphocytic Leukemia by High-Resolution Synchrotron Micro-Computed TomographyDOI 10.1101/2025.10.20.683519
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