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Digital PCR Linkage Analysis Resolves <i>Streptococcus pneumoniae</i> Signature from Commensal Interference in Saliva Samples: Identifying Wolves among Sheep in Wolf’s Clothing

2025-08-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Serotyping of Streptococcus pneumoniae (pneumococcus) is essential for evaluating the effects of conjugate polysaccharide vaccines on asymptomatic colonization (carriage) of vaccine-targeted capsular variants (serotypes). However, culture-independent application of molecular methods is hampered by genetic exchange between pneumococcus and oral streptococci co-residing within...

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Literature Corpus work
9d414740-937d-5f9f-9b2c-0a6501fc4fb4
DOI
10.1101/2025.08.02.25332851
Open publication

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Digital PCR Linkage Analysis Resolves <i>Streptococcus pneumoniae</i> Signature from Commensal Interference in Saliva Samples: Identifying Wolves among Sheep in Wolf’s ClothingDOI 10.1101/2025.08.02.25332851
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