Article
Evaluating methods for identifying and quantifying Streptococcus pneumoniae co-colonization using next-generation sequencing data.
Microbiology spectrum - 5 Dec 2024
Hackman Jada, Hibberd Martin L, Swarthout Todd D, Hinds Jason, Ashall James, Sheppard Carmen, Tonkin-Hill Gerry, Gould Kate, Brown Comfort, Msefula Jacquline, Mataya Andrew A, Toizumi Michiko, Yoshida Lay-Myint, French Neil, Heyderman Robert S, Flasche Stefan, Kwambana Brenda, Hué Stéphane
Abstract excerpt
Detection of multiple pneumococcal serotype carriage can enhance monitoring of pneumococcal vaccine impact, particularly among high-burden childhood populations. We assessed methods for identifying co-carriage of pneumococcal serotypes from whole-genome sequences. Twenty-four nasopharyngeal samples were collected during community carriage surveillance from healthy children in Blantyre, Malawi, which were then...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.