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It Takes Two to Tango: Combining Conventional Culture with Molecular Diagnostics Enhances Accuracy of <i>Streptococcus pneumoniae</i> Detection and Pneumococcal Serogroup/Serotype determination in Carriage

2021-11-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The specificity of molecular methods for the detection of Streptococcus pneumoniae carriage is under debate. We propose a procedure that increases the accuracy of molecular detection of live pneumococci in polymicrobial respiratory samples. <h4>Methods</h4> Culture and qPCR methods were applied to detect S. pneumoniae and pneumococcal serotypes in 1549 nasopharyngeal samples c...

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Literature Corpus work
82e2db65-3fda-5052-b835-b7dd31befd2e
DOI
10.1101/2021.11.26.21266900
Open publication

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It Takes Two to Tango: Combining Conventional Culture with Molecular Diagnostics Enhances Accuracy of <i>Streptococcus pneumoniae</i> Detection and Pneumococcal Serogroup/Serotype determination in CarriageDOI 10.1101/2021.11.26.21266900
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