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Avian H7N9 influenza viruses are evolutionarily constrained by stochastic processes during replication and transmission in mammals

2022-04-13

Abstract excerpt

H7N9 avian influenza viruses (AIV) have caused over 1,500 documented human infections since emerging in 2013. Although wild type H7N9 AIV can transmit by respiratory droplets in ferrets, they have not yet caused widespread outbreaks in humans. Previous studies have revealed molecular determinants of H7N9 AIV virus host-switching, but little is known about potential evolutionary constraints on this process. Here we...

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Literature Corpus work
9d328136-abf3-567f-aeed-fd048d0b8482
DOI
10.1101/2022.04.12.488056
Open publication

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Avian H7N9 influenza viruses are evolutionarily constrained by stochastic processes during replication and transmission in mammalsDOI 10.1101/2022.04.12.488056
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