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Apoptotic factors and mitochondrial complexes assist determination of strain-specific susceptibility of mice to Parkinsonian neurotoxin MPTP

2022-10-07

Abstract excerpt

Identification of genetic mutations in Parkinson’s disease (PD) promulgates the genetic nature of disease susceptibility. Resilience-associated genes being unknown till date, the normal genetic makeup of an individual may be determinative too. Our earlier studies comparing the substantia nigra (SN) and striatum of C57BL/6J, CD-1 mice and their F1-crossbreds demonstrated neuroprotective role of admixing, against th...

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Literature Corpus work
9d0c6c96-29bb-5c70-990f-e7c869e10328
DOI
10.1101/2022.10.05.511004
Open publication

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