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Screening for variable drug responses using human iPSC cohorts

2023-06-17

Abstract excerpt

<h4>ABSTRACT</h4> We have developed a laboratory-based drug screening platform that uses a cohort of human induced pluripotent stem cell (hiPSC) lines, derived from different donors, to predict variable drug responses of potential clinical relevance. This builds on recent findings that pluripotent hiPSC lines express a broad repertoire of gene transcripts and proteins, whose expression levels reflect the genetic...

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Literature Corpus work
9d0bf911-a5cc-5da5-9e20-a5aa02cca8cf
DOI
10.1101/2023.06.16.545161
Open publication

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Screening for variable drug responses using human iPSC cohortsDOI 10.1101/2023.06.16.545161
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