Article

Disruption of the surfactant protein A receptor SP-R210 <sub>L</sub> (CD245α/MYO18Aα) alters respiratory function and iron sequestration in alveolar macrophages of aged mice

2021-04-14

Abstract excerpt

<h4>ABSTRACT</h4> Previous studies demonstrated that the host defense collectins, surfactant protein A and complement component 1q, modulate tissue-dependent macrophage activation, pathogen clearance, and regulatory macrophage functions through the receptor SP-R210, which consists of two isoforms SP-R210 L and SP-R210 S . These isoforms are encoded by alternatively spliced mRNAs of the Myo18a MYO18A gene in mi...

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Literature Corpus work: 9d05c477-4930-5983-9610-ec7d392ab2a6
DOI: 10.1101/2021.04.14.439860

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