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Article

The molecular pathogenesis of Epstein-Barr virus-associated B-cell lymphoproliferative disorders: a scoping review.

Expert review of hematology - 1 Jun 2026

Vets Johanna, Haest Xenia, Tousseyn Thomas

Abstract excerpt

Epstein Barr virus (EBV) latent proteins play a pivotal role in the pathogenesis of EBV-associated lymphoproliferative disorders (EBV LPDs) effectively substituting for oncogenic driver mutations. EBV-related lymphomas are mutationally distinct from their EBV-negative counterpart disease but undergo similar treatment. Advancing therapies for EBV LPDs require a better understanding of the molecular pathogenesis of...

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B-Lymphocytes
Epstein-Barr Virus Infections
BCL2 gene
BCL6 gene
MYC gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Herpesvirus 4, Human

Lymphoproliferative Disorders

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Identifiers

PMID: 41934612
DOI: 10.1080/17474086.2026.2655963

Genes

BCL2
BCL6
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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