Article

Genomes of <i>Leishmania</i> parasites directly sequenced from patients with visceral leishmaniasis in the Indian subcontinent

2019-06-19

Abstract excerpt

Whole genome sequencing (WGS) is increasingly used for molecular diagnosis and epidemiology of infectious diseases. Current Leishmania genomic studies rely on DNA extracted from cultured parasites, which might introduce sampling and biological biases into the subsequent analyses. Up to now, direct analysis of Leishmania genome in clinical samples is hampered by high levels of human DNA and large variation in par...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9cc6e63c-fb6b-509b-bfa2-75b173dee415
DOI: 10.1101/676163

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genomes of <i>Leishmania</i> parasites directly sequenced from patients with visceral leishmaniasis in the Indian subcontinentDOI 10.1101/676163Read

Genomes of Leishmania parasites directly sequenced from patients with visceral leishmaniasis in the Indian subcontinent.Semantic proximity Read

Selective whole-genome amplification reveals population genetics of<i>Leishmania braziliensis</i>directly from patient skin biopsiesSemantic proximity Read

Global genome diversity of the <i>Leishmania donovani</i> complexSemantic proximity Read

Direct genome sequencing of <i>Leishmania tropica</i> in tissues of Moroccan patients with cutaneous leishmaniasis reveals micro-focal transmission underlain by clonal and sexual reproduction modesSemantic proximity Read

Insights into Genetic Heterogeneity and Drug Resistance in Leishmania donovani of the Indian sub-continent from genomic dataSemantic proximity Read

Genome wide comparison of Leishmania donovani strains from Indian visceral leishmaniasis and para-kala-azar dermal leishmaniasis patientsSemantic proximity Read

Single locus genotyping to track Leishmania donovani in the Indian subcontinent: Application in Nepal.Semantic proximity Read

Genetic diversity and comparative genomics across Leishmania (Viannia) speciesSemantic proximity Read

Global genome diversity of the Leishmania donovani complex.Semantic proximity Read

Selective whole-genome amplification reveals population genetics of Leishmania braziliensis directly from patient skin biopsiesSemantic proximity Read

Genome-wide SNP and microsatellite variation illuminate population-level epidemiology in the Leishmania donovani species complex.Semantic proximity Read

Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent.Semantic proximity Read