Article
Genome-wide SNP and microsatellite variation illuminate population-level epidemiology in the Leishmania donovani species complex.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2012
Downing Tim, Stark Olivia, Vanaerschot Manu, Imamura Hideo, Sanders Mandy, Decuypere Saskia, de Doncker Simonne, Maes Ilse, Rijal Suman, Sundar Shyam, Dujardin Jean-Claude, Berriman Matthew, Schönian Gabriele
Abstract excerpt
The species of the Leishmania donovani species complex cause visceral leishmaniasis, a debilitating infectious disease transmitted by sandflies. Understanding molecular changes associated with population structure in these parasites can help unravel their epidemiology and spread in humans. In this study, we used a panel of standard microsatellite loci and genome-wide SNPs to investigate population-level diversity...
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