Article

Induction of Sertoli cells from human fibroblasts by NR5A1 and GATA4

2018-09-29

Abstract excerpt

Sertoli cells are essential nurse cells in the testis that regulate the process of spermatogenesis and establish the immune-privileged environment of the blood-testis-barrier (BTB). The induction of human Sertoli cells from fibroblasts could provide cellular sources for fertility and transplantation treatments. Here, we report the in vitro reprogramming of human fibroblasts to Sertoli cells and characterize these...

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Literature Corpus work: 9cb057b1-6987-510f-b03f-2e95a39f1c85
DOI: 10.1101/430900

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