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In Vitro Derivation of Functional Sertoli-Like Cells from Mouse Embryonic Stem Cells

14 Sept 2018

Abstract excerpt

Sertoli cells (SCs) in the mammalian testes are well known as supporting cells of spermatogenesis, but have recently become an attractive source of cell therapy because of their capacity for immune modulation and trophic effects. In order to increase their applicable efficacy, we demonstrate a novel differentiation method for mouse embryonic stem cell (ESC)-derived Sertoli-like cells (SLCs) via the intermediate...

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PMID: 30215278
DOI: 10.1177/0963689718797053

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