Article

HPDL is critical in human cortical development via regulation of mitochondrial functional properties

2025-05-01

Abstract excerpt

Human brain development is highly regulated by several spatiotemporal processes, which disruption can result in severe neurological disorders. Emerging evidence highlights the pivotal role of mitochondrial function as one of these fundamental pathways involved in neurodevelopment. Our study investigates the role of 4-hydroxyphenylpyruvate dioxygenase-like (HPDL) protein in cortical neurogenesis and mitochondrial a...

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Literature Corpus work: 9c7b22ef-c69a-5993-aeef-27213d2106f3
DOI: 10.1101/2025.04.28.651017

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