Article

Reactivation of an Embryonic Cardiac Neural Crest Transcriptional Subcircuit During Zebrafish Heart Regeneration

2025-01-17

Abstract excerpt

<h4>ABSTRACT</h4> During vertebrate development, the heart primarily arises from mesoderm, with crucial contributions from cardiac neural crest cells that migrate to the heart and form a variety of cardiovascular derivatives. Here, by integrating bulk and single cell RNA-seq with ATAC-seq, we identify a gene regulatory subcircuit specific to migratory cardiac crest cells composed of key transcription factors egr...

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Literature Corpus work: 9c692ff9-fb41-5378-bc16-883abef80e73
DOI: 10.1101/2025.01.16.633462

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