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An organ-wide spatiotemporal transcriptomic and cellular atlas of the regenerating zebrafish heart

19 Apr 2025

Abstract excerpt

Adult zebrafish robustly regenerate injured hearts through a complex orchestration of molecular and cellular activities. However, this remarkable process, which is largely non-existent in humans, remains incompletely understood. Here, we utilize integrated spatial transcriptomics (Stereo-seq) and single-cell RNA-sequencing (scRNA-seq) to generate a spatially-resolved molecular and cellular atlas of regenerating...

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PMID: 40253397
DOI: 10.1038/s41467-025-59070-0

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