Article

Human Cytomegalovirus Strain Specific Differences in Protein Expression of Type I IFN Pathway Proteins Do Not Impact Virus Replication.

2025-08-18

Abstract excerpt

The type I interferon (IFN) response is crucial for cells to restrict viral replication during infection. Many viruses, including human cytomegalovirus (HCMV), have evolved mechanisms to antagonise the type I IFN response. We have previously observed an increase in protein expression of certain interferon stimulated genes (ISG) when comparing the high passage HCMV strain AD169 compared to the low passage strain HC...

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Literature Corpus work: 9c5e4672-e44c-5894-a156-f352d09f07c6
DOI: 10.1099/acmi.0.001104.v1

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